Expresión de búsqueda: RECEPTOR, EPHA1 
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Descriptor Inglés:   Receptor, EphA1 
Descriptor Español:   Receptor EphA1 
Descriptor Portugués:   Receptor EphA1 
Sinónimos Inglés:   EPHA1 Protein
EPHA1 Receptor Tyrosine Kinase
Eph Receptor
EphA1 Receptor  
Categoría:   D08.811.913.696.620.682.725.400.850.050
D12.776.543.750.630.500.050
Definición Inglés:   The founding member of the EPH FAMILY RECEPTORS. It was first cloned from an erythropoietin-producing human hepatocellular carcinoma cell line and is highly conserved among many mammalian species. Overproduction of the EphA1 receptor is associated with tumors and tumor cells of epithelial origin. It is also expressed at high levels in LIVER; LUNG; and KIDNEY; which is in contrast to many other members of the Eph receptor that are found primarily in tissues of the nervous system. 
Nota Histórica Inglés:   2003; use RECEPTOR, EPHA1 (NM) 1999-2002 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número del Registro:   37344 
Identificador Único:   D036082 

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